Systematic reviews
- Created by: jennymayg13
- Created on: 13-02-19 09:15
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- Systematic Reviews
- PICO
- Population
- Intervention
- Comparison
- Outcome
- GRADE
- Grading of Recommendations Assessment, Development, and Evaluation
- Grade down
- Imprecision
- 95% confidence interval
- Clinically important benefit
- Clinically important harm
- No clinically important difference
- 95% confidence interval
- Indirectness
- PICO
- Does it measure what it is supposed to?
- Inconsistency
- Heterogeneity
- Eye ball test
- Overlap of confidence intervals
- Chi2 p-value
- Probability it is by chance
- I2
- % it is not by chance
- Eye ball test
- Heterogeneity
- Risk of bias
- Generation of randomisation
- Allocation concealment
- Blinding
- Incomplete outcome data
- Selective outcome bias
- Publication bias
- Funnel Plots
- Asymmetry: Bite taken out of it?
- Funnel Plots
- Imprecision
- Grade up
- Large effect
- Confounders
- Dose response
- Certainty
- 4. High = Further research unlikely to change confidence in results
- 3. Moderate = Further research is likely to have an impact on results
- 2. Low = Further research is very likely to have an important impact on results
- 1. Very low = Very uncertain about results
- 2. Low = Further research is very likely to have an important impact on results
- 3. Moderate = Further research is likely to have an impact on results
- 4. High = Further research unlikely to change confidence in results
- Grade down
- From evidence to recommendations
- Balance of benefit and harm
- Feasibility
- Resource implications/ costs
- Recommendation
- Grading of Recommendations Assessment, Development, and Evaluation
- Bias
- Generation of randomised sequence
- Flipping a coin
- Computer generated sequence
- Random number tables
- Allocation concealment
- Patients and investigators don't who receives which intervention is being allocated
- Sequentially numbered opaque envelopes
- Identical containers
- Blinding
- Outcome not influenced
- Incomplete outcome data
- Missing data
- Selective outcome bias
- Selective outcome reporting
- Generation of randomised sequence
- Structure
- Background and objectives
- Eligibility criteria
- Methods
- Description of included trials
- Risk of bias
- Outcome data analysis and results
- Discussion and conclusion
- Outcome data analysis and results
- Risk of bias
- Description of included trials
- Methods
- Eligibility criteria
- Background and objectives
- PICO
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