Metabolism.

Created by: rachelrhubarb11
Created on: 07-05-16 22:33


	Metabolism.
	Similarities Metabolic pathways Can work aerobically, producing 36 ATP total. In anaerobic conditions, only glycolysis works, therefore 2 ATP's are produced only. However glycolysis requires 2 ATP anyway. Cellular respiration TCA and ETC occur in the mitochondria	Differences Glycolysis works aerobically and anaerobically, TCA only works aerobically Glycolysis uses 2 ATP, Kreb's does not require ATP Linear means you start with one product and produce a different product. They use each product before as a substrate. Glucose creates pyruvate. Circular means you start with one product and end with the same product, each metabolite is regenerated. In TCA oxaloacetate begins Krebs. Glycolysis breaks down sugars Krebs uses Acetyl CoA which is a product of glycolysis, fatty acid metabolism or amino acid metabolism. Glycolysis is regulated when ATP levels are too high. The ATP binding sites divert to allosteric pathways, shutting down the enzyme. Krebs is regulated by high levels of ATP, NADH and Acetyl CoA slowing down pyruvate dehydrogenase. When ATP is low, AMP can trigger faster production. ETC only works when oxygen is available and is the highest yielder of ATP. ETC creates a proton gradient from high to low that drives energy production and requires no energy to do so. The momentum creates the energy
	Overall comparison Glycolysis is a linear pathway that follows steps where each product is used as the next substrate. Glycolysis requires 2 ATP to produce 4 ATP, therefore having net total of 2 ATP. The end product of glycolysis is 2 pyruvate. Glycolysis can work aerobically and anaerobicallyThe two pyruvate molecules produced by glycolysis enter the circular pathway, TCA cycle. The TCA requires oxygen for oxidation, therefore only works aerobically. 3NADH, 1 FADH, 1 GTP and 2 CO2 are released. However this cycle goes round twice as there are two pyruvate molecules, therefore 2 ATP are made in total.The Electron Transport Chain target is to break down the NADH and FADH produced by TCA cycle. The ETC using a concentration gradient to produce ATP. ATP is produced when H+ is moved through the concentration gradient by the enzyme ATP-synthase. ETC produces 32 ATP

Metabolism.

Similarities

Metabolic pathways
Can work aerobically, producing 36 ATP total.
In anaerobic conditions, only glycolysis works, therefore 2 ATP's are produced only. However glycolysis requires 2 ATP anyway.
Cellular respiration
TCA and ETC occur in the mitochondria

Differences

Glycolysis works aerobically and anaerobically, TCA only works aerobically
Glycolysis uses 2 ATP, Kreb's does not require ATP
Linear means you start with one product and produce a different product. They use each product before as a substrate. Glucose creates pyruvate.
Circular means you start with one product and end with the same product, each metabolite is regenerated. In TCA oxaloacetate begins Krebs.
Glycolysis breaks down sugars
Krebs uses Acetyl CoA which is a product of glycolysis, fatty acid metabolism or amino acid metabolism.
Glycolysis is regulated when ATP levels are too high. The ATP binding sites divert to allosteric pathways, shutting down the enzyme.
Krebs is regulated by high levels of ATP, NADH and Acetyl CoA slowing down pyruvate dehydrogenase. When ATP is low, AMP can trigger faster production.
ETC only works when oxygen is available and is the highest yielder of ATP.
ETC creates a proton gradient from high to low that drives energy production and requires no energy to do so. The momentum creates the energy

Overall comparison

Glycolysis is a linear pathway that follows steps where each product is used as the next substrate. Glycolysis requires 2 ATP to produce 4 ATP, therefore having net total of 2 ATP. The end product of glycolysis is 2 pyruvate. Glycolysis can work aerobically and anaerobicallyThe two pyruvate molecules produced by glycolysis enter the circular pathway, TCA cycle. The TCA requires oxygen for oxidation, therefore only works aerobically. 3NADH, 1 FADH, 1 GTP and 2 CO2 are released. However this cycle goes round twice as there are two pyruvate molecules, therefore 2 ATP are made in total.The Electron Transport Chain target is to break down the NADH and FADH produced by TCA cycle. The ETC using a concentration gradient to produce ATP. ATP is produced when H+ is moved through the concentration gradient by the enzyme ATP-synthase. ETC produces 32 ATP

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Metabolism.

Metabolism.

Similarities

Differences

Overall comparison

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