Meehl (1962) originally proposed that both a vulnerability to schizophrenia and a stress-trigger are necessary in order to develop the condition.
Meehl suggested that the vulnerability is genetic (the result of a 'schizogene'), causing a sensitive personality.
Chronic environmental stress, for example, having a schizophrenogenic mother, results in the onset of schizophrenia, even if they experienced a chronically stressful upbringing.
Both aspects of diathesis-stress must be present to develop the disorder.
The modern understanding of diathesis-stress is slightly different. It is now recognised that the vulnerability could be genetic or environmental (for example, a traumatic event in early childhood). The stress-trigger could be environmental or biological (for example, smoking cannabis is linked with schizophrenia).
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