Enzymes week one - Synch class

Hydrolases 

• Hydrolases break down other molecules.
• They are both in the digestive system.
• Both use water to break down molecules.
• Both produced by pancreas.
• If deficient in either causes illness. 
• Essential for breakdown.
• Enzyme activity is based on pH and place where it is found. 
• Protaese and amylase are both used in the medication.

Isomerase

• Isomerase is an enzyme that catalyses the conversion of a specified compound to an isomer.
• They're involved in structural rearrangements of molecules.  
• Isomerase catalyse changes that happen within one molecule
• ligases catalyses the joining or ligation of two large molecules by forming a new chemical bond usually with accompanying hydrolysis of a pendant small chemical group
• Isomerases catalyse reactions across many biological processes, such as in glycolysis and carbohydrate metabolism.
• Effects: TPI deficiency can lead to disorder such as hemolytic anemia, neurological problems, infection and muscles weakness which can cause abnormalities such as heart and breathing problems.  

Fumarase and Carboxylases (hydro-lyase)

• Catalyses the breakdown of larger molecules into smaller molecules with addition of water.
• Class of enzyme performs as biochemical catalysts that use water to break a chemical bond, which typically results in dividing a larger molecule to smaller molecules (catalyzes hydrolysis reaction)
• Hydrolases - split molecules by addition of water
• Lyases - split molecules without addition of water
• Function of most hydrolases is digestive - to break down nutrients into smaller units for digestion. 
• Facilitate intramolecular rearrangements in which bonds are broken and formed.
• Classified as alpha…