virology case study
- Created by: luceebrown
- Created on: 09-01-20 10:08
Case Studies:
biology of small pox and why it is now extinct:
- wide endemic in europe and asia
- exclusively human and spread person - person
- starts as a respiratory infection
- dsDNA
immunisations against smallpox:
innoculation against smallpox using live virus in the 1500's
edward jenners vaccination with cow pox
now = vaccination with vaccinia virus
eradiciation was possible because:
- it was exclusive to humans
- no hidden carriers of the disease
- only one serotype
- vaccination was 100% successful
the biology of herpesvirus:
- dsDNA with relatively large genome
- lifelong infection
latent cycle = few viral proteins expressed and no virions produced
lytic cycle = all viral proteins expressed and virions produced
2 strands of herpesvirus:
HSV 1 = infects nerve cells - primary infection is cold sores - reactivates due…
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