Cancer 2.0 / 5 based on 1 rating ? BiologyjjUniversityAll boards Created by: Broken RoseCreated on: 15-06-15 22:49 What is neoplastic transformation? Conversion of a normal cell to a malignant cell 1 of 5 BCR ABL kinases don't Initiate denaturing of checkpoint proteins 2 of 5 What does the tumour supressor gene do? They code for proteins that control cell cycle progression/proliferation (many of which are check point genes. 3 of 5 How is proliferation controlled in normal cells Activate oncogenes transiently (i.e for a short by mitogens) and INactivate tumour suppressor genes transeintly 4 of 5 How can Mitotic crossover play a role in cancer? It is an event where a cancer causing reccesive allele may be expressed and thus predispose the cell causing development of cancer 5 of 5
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