Cushing's Syndrome

?
Cushing's syndrome is a condition caused by having too much of which hormone in the body?
Cortisol
1 of 9
Which type of drug is the most common cause of this condition?
Steroids
2 of 9
Why is this?
Steroids contain a synthetic version of cortisol
3 of 9
Very rarely, this condition can be caused by a growth (tumour) in the pituitary gland in the _____ or a tumour in 1 of the _______ glands above the kidneys.
brain, adrenal
4 of 9
These tumours are most common in women over 65.
True/False?
False
- More common in young women
5 of 9
Typical clinical findings include:
Truncal obesity
Buffalo hump
Moon face
Oedema
Striae
Proximal muscle wasting
6 of 9
Metyrapone, mitotane and ____________ all directly inhibit glucocorticoid synthesis and secretion in the _______ gland.
ketoconazole
7 of 9
What is a complication of cushings syndrome affecting bones?
Osteoporosis
8 of 9
Why does excess cortisol increase risk of osteoporosis?
Interferes with osteoblast formation
9 of 9

Other cards in this set

Card 2

Front

Which type of drug is the most common cause of this condition?

Back

Steroids

Card 3

Front

Why is this?

Back

Preview of the front of card 3

Card 4

Front

Very rarely, this condition can be caused by a growth (tumour) in the pituitary gland in the _____ or a tumour in 1 of the _______ glands above the kidneys.

Back

Preview of the front of card 4

Card 5

Front

These tumours are most common in women over 65.
True/False?

Back

Preview of the front of card 5
View more cards

Comments

No comments have yet been made

Similar Medicine resources:

See all Medicine resources »See all Medicine resources »