FCB 0.0 / 5 ? BiologyEXAM REVISIONUniversitySQA Created by: rkerri200Created on: 13-08-19 12:08 Which lipid is negatively charged AND predominantly located in the cytosolic leaflet of the plasma membrane? Phosphatidylserine 1 of 36 Which is NOT a membrane constituent? Proteoglycan 2 of 36 Which of the following comments about LIPID-ANCHORED membrane proteins is TRUE? The hydrocarbon chain of the lipid anchor is embedded in the lipid bilayer 3 of 36 Which of the following terms correctly describes the type of transport mediated by antiporters? Secondary active transport 4 of 36 What describes the speed of transport (fastest first) of ATPases, carriers and ion channels Ion channels, carriers, ATPases 5 of 36 What plays the major role in maintaining plasma membrane potential? K+ leak channel 6 of 36 What undergoes targeted (specific) transcytosis in intestinal cells? Maternal antibodies 7 of 36 Which cells can mediate phagocytosis? Macrophages 8 of 36 What is the pH of a lysosome? pH 5.0 9 of 36 What CAN be employed to restrict the mobility of plasma membrane proteins? Tethering to the cytoskeleton 10 of 36 In which vesicles would you expect to see a bacteria ultimately destined for lysosomal degradation? Phagosome 11 of 36 What cannot diffuse directly (passively) across the plasma membrane? Na+ 12 of 36 What types of transport is mediated by ion channels? Facilitated diffusion 13 of 36 What term describes ‘cell drinking’ Pinocytosis 14 of 36 Which ATPase operates in ‘reverse’ to generate ATP? F-type ATPase 15 of 36 Receptor mediated endocytosis involves hydrolysis of? GTP 16 of 36 What is the fate of the EGF receptor following endocytosis? Degradation in lysosomes 17 of 36 Which phosphoinositide is involved in actin polymerisation and pseudopod formation? PIP2 18 of 36 How are senescent red blood cells removed from the body? Phagocytosis 19 of 36 Which phospholipids can stimulate phagocytosis? Phosphatidylserine 20 of 36 The mouse represents an excellent model for human disease because: It has a short breeding cycle 21 of 36 Epithelial tissue comprises cells that are: Line the lumen of tissues exposed to the external environment 22 of 36 To isolate and culture mammalian cells you need to: Maintain the isolated cells isotonic media that is supplemented with serum to provide growth factors 23 of 36 A western blot relies on: Separation of proteins by SDS PAGE followed directly by probing with specific antibodies targeted to the protein of interest. 24 of 36 The principles of immunofluorescence dictate that: The fluorescent probe absorbs light at one wavelength and emits it at a longer wavelength 25 of 36 what components of the cytoskeleton have catalytic activity? Microtubules and microfilaments have catalytic activity 26 of 36 What are lamins? Lamins are intermediate filaments found in the nucleus 27 of 36 Intermediate filaments : Have no enzymatic activity 28 of 36 Microfilaments are composed of : Two protofilaments composed of G actin with ATP hydrolysis 29 of 36 The nucleation core of microtubules is: A preformed gamma tubulin ring that is located near the centrosomes 30 of 36 Contractile bundles of microfilaments are associated with: Anti-parallel alignments of actin filament associated with actinin dimers 31 of 36 Myosin II is : A plus end motor protein that interacts with anti-parallel alignments of actin microfilaments 32 of 36 Kinesins are proteins that Have two globular heads with ATP activity, one of which is always associated with the microtubule 33 of 36 Stathmin is a protein that: Traps alpha/beta tubulin dimers in the cytoplasm and restricts microtubule growth 34 of 36 Treadmilling ensures that: The rate of addition of actin monomers at the plus end equals the rate of loss at the minus end 35 of 36 Within a neuron microfilaments are: Are highly clustered tighter into parallel arrays held together by MAP2 and Tau proteins 36 of 36
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