Genetic Explanations

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  • Created by: Mahdi2420
  • Created on: 30-11-20 15:25
Genetics Explanation of Schizophrenia
Part of the biological explanation, suggests that genetics are part of the origin of SZ.
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Family Studies
Family studies find individuals who have schizophrenia and determine whether their biological relatives are similarly affected more often than non-biological relatives. There are two types of twins – identical (monozygotic) and fraterna
Gottesman (1991) found that MZ twins have a 48% risk of getting schizophrenia whereas DZ twins have a 27% risk rate. This is evidence that the higher the degree of genetic relativeness, the higher the risk of getting schizophrenia.
However, Monozygotic t
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Adoption Studies
Due to difficulties of disentangling genetic and environmental influences for individuals who share genes and environment, studies of genetically related individuals who have been reared apart are used.
Tienari et al. (2000)
164 adoptees whose biological mothers had been diagnosed with schizophrenia, 11 (6.7%) also received a diagnosis of schizophrenia, compared to 4 (2%) of the 197 control adoptees, who were born to non-schizophrenic mothers. These fin
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A key assumption of adoption studies is that it is random. Joseph claims that this is unlikely to be the case because adoptive parents are informed of the child's genetic background before adoption. This might have an impact later because only certain peo
.
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Candidate genes for schizophrenia have also been found. Individual genes are believed to be associated with the risk of inheritance.
SZ is polygenic as there are multiple genes and combinations which are responsible.
Ripke et al. (2014)study combining all previous data from genome-wide studies of schizophrenia. The genetic make-up of 37,000 patients was compared to the genetic make-up of 113,000 controls.
108 separate genetic variations were associated with an increa
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Card 2

Front

Family Studies
Family studies find individuals who have schizophrenia and determine whether their biological relatives are similarly affected more often than non-biological relatives. There are two types of twins – identical (monozygotic) and fraterna

Back

Gottesman (1991) found that MZ twins have a 48% risk of getting schizophrenia whereas DZ twins have a 27% risk rate. This is evidence that the higher the degree of genetic relativeness, the higher the risk of getting schizophrenia.
However, Monozygotic t

Card 3

Front

Adoption Studies
Due to difficulties of disentangling genetic and environmental influences for individuals who share genes and environment, studies of genetically related individuals who have been reared apart are used.

Back

Preview of the front of card 3

Card 4

Front

A key assumption of adoption studies is that it is random. Joseph claims that this is unlikely to be the case because adoptive parents are informed of the child's genetic background before adoption. This might have an impact later because only certain peo

Back

Preview of the front of card 4

Card 5

Front

Candidate genes for schizophrenia have also been found. Individual genes are believed to be associated with the risk of inheritance.
SZ is polygenic as there are multiple genes and combinations which are responsible.

Back

Preview of the front of card 5

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