Menstrual cycle! 0.0 / 5 ? OtherMidwiferyUniversityNone Created by: Izzy2807Created on: 05-10-19 20:51 What are the 4 stages of the menstrual cycle? Menstration (5-7 days), Follicular Phase (6-7 days), Ovulation (1 day), Luteal Phase (12-14 days) 1 of 21 What hormone does the hypothalamus release? Gonadatropin Releasing Hormone (GnRH) 2 of 21 GnRH travels through the blood stream to what gland? What does this stimulate? Anterior Pituitary Gland, stimulating the APG to release Follicle Stimulating Hormone (FSH) and Luteinising hormone (LH) 3 of 21 Where do FSH and LH travel to? The ovaries (where the ovum are), entering via ovary capillaries 4 of 21 What does FSH stimulate (in the ovaries)? Follicle maturity 5 of 21 Only some ovum in the ovaries mature each month, how many will ovulate? Only one 6 of 21 Whilst the follicles mature, what hormone do they release? Oestrogen 7 of 21 What feedback loop does oestrogen produce (at low concentrations) for LH? A negative feedback loop for LH 8 of 21 When oestrogen levels are high, what level is FSH? Low! A negative feedback loop! So when oestrogen levels are low, FSH levels are high. 9 of 21 What does oestrogen stimulate? Endometrial growth 10 of 21 After 10 days, oestrogen levels rise, what feedback loop does this stimulate for LH (at high concentrations)? A positive feedback loop for LH! 11 of 21 The release of LH triggers what? Ovulation of the mature follicle 12 of 21 What does the ovulation of the mature follicle do? It releases the oocyte (immature ovum) 13 of 21 After ovulation, what happens to the mature follicle? It turns into a corpus luteum, now in the luteal phase 14 of 21 What 3 hormones does the corpus luteum secrete? Oestrogen, Inhibin and Progesterone 15 of 21 Oestrogen and Progesterone stimulate the thickening of what lining? Endometrial lining 16 of 21 As the CL degenerates, all hormone generation degenerates too, what effect does this have on the cycle? The decrease in progesterone will no longer have a negative feedback effect on GnRH, so a new cycle can start! 17 of 21 What specific role does progesterone have in the cycle? It has a negative feedback effect on the hypothalamus for GnRH release 18 of 21 What does inhibin do (secreted when the corpus luteum degenerates) It inhibits FSH secretion 19 of 21 What are the 3 stages of the endometrial cycle/development? Menstruation (days 1-5), Proliferate phase (days 6-14), Secretory phase (days 15-28) 20 of 21 What happens at the menstrual, proliferate and secretory phase? M: endometrial lining degenerates and is shed. P: endometrium starts to regenerate S: endometrium regenerates rapidly and thickens 21 of 21
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