TCA cycle 3.0 / 5 based on 1 rating ? BiologyUniversityOther Created by: jessicaCreated on: 18-12-12 09:33 What is the first step in the TCA cycle? Oxaloacetate undergoes carboxylation and hydrolysis forming citrate 1 of 16 What enzyme is used in the first step? Citrate synthase 2 of 16 What happens in the second step? Citrate is dehydrated to cis-Aconitate, then hydrated into Isocitrate 3 of 16 What enzyme is used in the second step? Aconitase 4 of 16 What happens in the third step? Isocitrate undergoes dehydrogenation to oxalosuccinate, then decarboxylated to Alpha Ketoglutarate 5 of 16 What enzyme is used in the third step? Isocitrate dehydrogenase 6 of 16 What happens in the fourth step? Alpha Ketoglutarate undergoes dehydrogenation then decarboxylation forming succinyl CoA 7 of 16 What enzyme is used in the fourth step? Alpha Ketoglutarate dehydrogenase complex 8 of 16 What happens in the fifth step? Sucinyl CoA undergoes substrate level phosphorylation forming succinate 9 of 16 What enzyme is used in the fifth step? Succinyl CoA synthetase 10 of 16 What happens in the sixth step? Succinate undergoes oxidation forming fumarate 11 of 16 What enzyme is used in the sixth step? Succinate dehydrogenase 12 of 16 What happens in the seventh step? Fumarate undergoes hydration forming L-Malate 13 of 16 What enzyme is used in the seventh step? Fumarase 14 of 16 What happens in the eighth step? L-Malate undergoes oxidation forming oxaloacetate 15 of 16 What enzyme is used in the eighth step? Malate dehydrogenase 16 of 16
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