the endocrine system

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  • Created by: asifakhan
  • Created on: 05-01-21 12:01
what is diabetes insipidus?
where large amounts of urine are produced which causes extreme thirst
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what is cranial diabetes insipidus?
where the hypothalamus does not make enough ADH
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what is nephrogenic diabetes insipidus?
where the kidneys do not respond to ADH
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which corticosteroid exerts the highest mineralocorticoid activity?
fludrocortisone
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what is used for hypopituitarism?
hydroocortisone
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what is the warning associated with ketoconazole?
life threatening hepatotoxicity
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when are statins given during diabetes?
primary prevention in type 1 diabetes
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when does treatment for gestational diabetes stop?
after birth
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when do the requirements for insulin increase?
when on holiday
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what happens if insulin is found to be frozen?
discard
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how does metformin work?
decreases liver gluconeogenesis and increases peripheral use
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can glibenclamide be used in pregnancy?
yes during 2nd and 3rd trimester
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what is a side effect of rapaglinide?
visual disturbance
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when is acarbose used?
reserved for use when other oral hypoglycaemic cannot be taken
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how is type 2 diabetes diagnosed?
6.5% (48mmol/mol) or above to diagnose type 2 diabetes
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what is the pre prandial blood glucose target in type 2 diabetes?
4.7mmol/L
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what is the post prandial blood glucose target in type 2 diabetes?
<9mmol/L
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what is the target for hypertension without complications in diabetic patients
140/80mmHG
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what is the cholesterol target for diabetic patients?
<4mmol/L
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why aren't chocolate biscuits good for hypoglycaemic emergencies?
fat delays glucose absorption
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what is the treatment and prophylaxis for corticosteroid induced osteoporosis?
oral corticosteroid for _<3 months, low trauma fracture
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what is the first line for the prophylaxis and treatment of post menopausal osteoporosis?
alendronic acid
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what is an important side effect regarding bisphosphonates? what is the main counselling point regarding this?
oesophagitis, strictures, ulcers and erosions - stop and report dysphagia, new or worsening heartburn or retrostemal pain
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what is tibolone used for?
vaginal atrophy
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what is an alternative to tibolone?
clonidine
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why is clomifene only used for 6 cycles only?
risk of ovarian cancer
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what is the first line treatment for HYPERthyroidism?
carbimazole
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what is a side effect of propylthiouracil?
hepatotoxicity
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is the blocking replacement regimen for hyperthyroidism safe in pregnancy?
no, contraindicated
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when you should you take a gliptin (DP-4 inhibitor)?
30 mins before main meal
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what is the range for type 2 diabetes diagnosis?
48mmol/mol
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what reference would indicate hypoglycaemia?
<4mmol/L
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Other cards in this set

Card 2

Front

what is cranial diabetes insipidus?

Back

where the hypothalamus does not make enough ADH

Card 3

Front

what is nephrogenic diabetes insipidus?

Back

Preview of the front of card 3

Card 4

Front

which corticosteroid exerts the highest mineralocorticoid activity?

Back

Preview of the front of card 4

Card 5

Front

what is used for hypopituitarism?

Back

Preview of the front of card 5
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