Step 1 isn't a major control point because it is also part of the PPP, the control is just for glycolysis hence why the major control point is at step 3 instead of step 1
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Where does the PPP take place?
In the cytoplasm (cytoplasm and chloroplasts in plants)
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Step 1 of PPP- after glucose has been converted to glucose-6P (Oxidative stage)
Interconvert between isomers, (Enzyme: Ribose-5P isomerase), product: Ribose P and Xylulose-5P
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Stage 5 (non-oxidative stage)
Interconvert between epimers, (Enzyme: Ribose-5P epimerase), product: Ribose-5P
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Stage 6 (non-oxidative stage)
Takes 2C unit from top ketose and adds it to aldose, reversible, (Enzyme: Transketolase), product: an aldose -2C (Sedohept-7P) and a ketose +2C (G3P)
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Stage 7 (non-oxidative stage)
Takes 3C unit from top ketose and gives it to an aldose, reversible, (Enzyme: Transaldolase), product: a ketose +3C (Fructose-6P) and an aldose -3C (Erythrose-4P)
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What molecules from the PPP are used for lipid synthesis?
The 2 NADPH+H+ molecules (One from stage 1, one from stage 3)
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What molecules from the PPP are used for central metabolism?
Xylose-5P, G3P and fructose-6P
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What molecule from the PPP is used for nucleotides?
Ribulose-P
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Which molecule from the PPP is used for aromatic amino acids?
Erythrose-4P
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Other cards in this set
Card 2
Front
What is an alternate route?
Back
Pentose phosphate pathway
Card 3
Front
When does the PPP branch off from the major metabolic fate?
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